Research & Clinical Studies
Endocrine & Diabetes Plus Clinic participates in research to advance endocrine and metabolic care. Learn about our research interests.
Our Research Mission
At Endocrine & Diabetes Plus Clinic of Houston, we believe that clinical research is essential to advancing patient care. Our physicians have a strong track record of academic and clinical research — particularly in diabetes, thyroid disorders, and metabolic conditions.
Dr. Kim has published peer-reviewed research in leading medical journals, with work focusing on genetic prediction of Type 2 diabetes, cardiovascular effects of incretin therapy, and the role of hematopoietic cells in diabetes. Dr. Varughese's fellowship research focused on diabetes medication and its effects on inflammation and endothelial dysfunction.
Areas of Research Interest
- Type 1 and Type 2 diabetes — treatment outcomes and emerging therapies
- Thyroid cancer surveillance and management
- Continuous glucose monitoring (CGM) technology effectiveness
- Insulin pump therapy in Type 1 diabetes
- Metabolic syndrome and cardiovascular risk reduction
- Fatty liver disease (MAFLD/MASLD) and its endocrine connections
- Telemedicine models for endocrine care access
- Osteoporosis and bone density management
Selected Publications
Kim J, Kim J, Kwak MJ, Bajaj M. Genetic prediction of type 2 diabetes using deep neural network. Clin Genet, 2018;93(4):822–829. PMID: 29136281.
Buras ED et al. Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice. FASEB J, 2015;29(8):3537–3548. PMID: 25953849.
Kim J, Samson SL. Cardiovascular effects of incretin therapy in diabetes care. Metab Syndr Relat Disord 2014;12(6):303–310. PMID: 24842063.
Kojima H, Kim J, Chan L. Emerging role of hematopoietic cells in diabetes. Trends Endocrinol Metabol 2014;25(4):178–187. PMID: 24507996.
Kim J, Chae YK, Chernoff A. The risk for coronary heart disease according to insulin resistance with and without type 2 diabetes. Endocr Res 2013;38(4):195–205. PMID: 23425058.
Participate in Research
From time to time, our clinic participates in clinical studies that may be open to eligible patients. If you are interested in learning about research opportunities, please speak with your provider at your next visit or call us at 832-968-7003.